Although there are experimentally induced models of glaucoma in rats and mice, the exceptional endpoint for studies using these species is typi- cally to identify specific molecular or cellular alterations affected in the pathogenesis of the glaucoma and not to determine the efficacy of anti-glaucoma drugs intended owing use in humans. Visit with Xenobiotic transporters Antioxidant comeback, 140 Anuria, 180 Apaf-1 post in apoptosome, 113 muffling through Hsp70, 139 AP endonucleases, duty in inferior excision restore, 238 Apoptosis definition and determining, 112 induction via DNA impair, 238 instrinsic pathway, 115 situation in tippler cardiac myopathy, 279 duty of caspases, 113 Aristolochic acid enzymatic nitroreduction, 250 role in Balkans endemic nephropathy, 248 Aromatic amines, 306 historical significance, 11 Arsenic, 7, 9 society in tobacco smoke, 298 Arylhydrocarbon receptor (AhR) inducing ligands, 132 structural features, 131 toxicity receptor archetype, 94 Aryl hydrocarbon receptor atomic translocator (ARNT), 131 Asbestos asbestosis in exposed workers, 254 contrariety of corporeal forms and human convention, 253 historical moment, 11 ATF6 activation pathway, 145 role in ER stress answer, 145 ATF4, situation in ER significance return, 145 Azidothymidine (AZT), hepatotoxic potential, 166 B Groundwork excision repair (BER), 238 Bcl-2, role in apoptosis, 113 Benzene, bond with leukemia, 74 Benzoquinone, 74 Biliary excretion, account of mass, 82 Bioactivation contribution